Fyodor Yurchikhin, Karen Nyberg and Luca Parmitano lift off on their six hour flight to the International Space Station
The Soyuz rocket carrying Fyodor Yurchikhin, Karen Nyberg and Luca Parmitano lifted away from the Baikonur Cosmodrome at 02:31 local time on Wednesday (20:31 GMT Tuesday).
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Georgian Yurchikhin and American Nyberg have both been into space before. Italian Parmitano is a first-timer.
They arrived at the orbiting platform five hours and 46 minutes later.
Their Soyuz capsule was using a new flight profile that dramatically reduces the rendezvous time from the traditional two days.
It is technically more difficult and requires some very precise orbital adjustments, but it is deemed to be easier on the crew because it means they do not have to spend so long inside their cramped vehicle.
Leak and pressure checks were conducted following docking at the station, with a hatch opening at 04:14 GMT.